San Franciso Reports First Clade I Monkeypox Case

Last month, my colleague Mary Chastain reported that the New York City Health Department announced the city’s first case of the severe monkeypox strain, Clade 1.

I have been following the spread of this particular virus for some time. Clade I mpox is a more severe strain of the mpox virus endemic to Central Africa, associated with higher fatality rates (up to 10% historically) than Clade II. It includes sub-clades Ia (associated with animal-to-human transmission) and Ib (linked to recent, more rapid sexual transmission).

Now, a case is being reported in San Francisco.